Service quality is an issue that organizations must address, particularly service-oriented organizations. Service quality will indicate whether the organization achieved the requisite level of quality based on the expectations of the organization and the students. This study focuses on determining the effect of service quality on students’ satisfaction in the University Health Center at Universiti Utara Malaysia. The type of research used was quantitative research and assessed the five dimensions of service quality (independent variables), which are tangible, reliability, responsiveness, assurance, and empathy. This study employed a cluster sampling technique. The questionnaire was distributed to students of Universiti Utara Malaysia who stayed in Sime Darby Student Residential Hall. There were 117 students responded to the questionnaire. The SPSS version 29 was used to analyse the data. The findings from the analysis reveal that tangible, reliability, responsiveness, assurance, and empathy have a significant effect towards students’ satisfaction. In addition, the responsiveness assurance, and empathy variables are highly significant in determining students’ satisfaction. Practical or theoretical implications for comprehending the characteristics of the effect of tangible, reliability, responsiveness, assurance, and empathy would make academic and service providers be more concern about students’ satisfaction to improve service quality in the University Health Center.