The aims of this research are to examine the influence of Profitability, Collateral, and Non-Debt Tax Shields on the Capital Structure. This research was conducted on Manufacturing Food and Beverages companies listed on the Indonesia Stock Exchange in 2016-2020. This study used a purposive sampling technique with a few samples that meet the criteria of 19 companies with 95 data. The main results show that Profitability has a statistically negative effect on profitable companies but insignificant for companies who experienced falling-of in profits. Collateral has a statistically positive and significant effect because a high level of Tangible Assets can give more access for a company to external finance. And Non-Debt Tax Shields has a statistically negative and significant effect because benefits that come from debt which is tax deduction can also be obtained from Depreciation.