Burns are injuries that result from direct contact or exposure to sources of heat, electricity, chemicals, or radiation. The purpose of this study was to determine the effect of kerokot stem extract ointment (Lygodium microphyllum Cav. R. Br.) On burn healing and to determine the concentration of kerokot stem extract which was the most effective in healing burns in white rats. This research method is an experimental study conducted on 5 groups of mice consisting of negative control of ointment bases, positive control of MEBO® ointment, variations in the concentration of kerokot stem ointment extracts 10%, 15%, 25%. The treatment was given after making burns as much as 1 time a day for 28 days and seen the process of healing burns by measuring the diameter of the wound, analyzing the wound area data in each treatment group using statistical analysis with Kruskal Wallis test. The results showed that the kerokot stem extract ointment formulation had fulfilled the evaluation requirements of physical characteristics including organoleptic, homogeneity, pH, spreadability, viscosity and provided a second degree burn healing effect on white rats, and the kerokot stem extract ointment preparation was the most effective in wound healing at concentration of 25%.

Keywords: Kerokot Rod (Lygodium microphyllum Cav. R. Br.), Burns, Ointment Evaluation, Ointment Formulation